IndraLab

Statements


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"Alcohol generally suppresses c-fos activity within the septum and decreases catecholamine levels after both acute and chronic treatment [34, 35, 57, 58] ."
| DOI

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"The acute EtOH induced c-fos induction in the medial Amy was inhibited by the MEK inhibitor, U0126 238."

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"For example, a marked decrease in c-fos levels was observed in the striatum of rats chronically treated with ethanol (Yang et al., 1998), and no increase in c-fos immunoreactivity was observed upon NMDA treatment of rats that have been chronically treated with vapor ethanol (Hardy et al., 1999)."

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"We have previously reported that rats selectively bred for alcohol preference show altered Arrb2 mRNA levels in several brain regions compared to their non preferring counterparts, and mice lacking the Arrb2 gene exhibit reduced alcohol induced locomotion and c-fos activation in the shell of nucleus accumbens in response to a low dose of alcohol, suggesting impaired alcohol reward."

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"A previous study found that 1 g/kg of alcohol decreased c-Fos immunoreactivity in the insula of male rats, and that insular cortex inactivation partially substituted for the discriminative stimulus effects of this alcohol dose (Jaramillo et al., 2018)."

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"Using slot-blot hybridization, significant induction of c-fos mRNA after restraint stress was demonstrated both in hippocampus and cortex, but prior alcohol exposure specifically attenuated c-fos induction only in the hippocampus."

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"Experiment 4: Inhibition of the EWcp and ethanol-induced c-Fos in the EWcp."

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"Whereas administration of EtOH per se decreased slightly the number of c-Fos + cells compared to sal-S (18.5 +/- 0.5 cFos + neurons/10 4 mum 2), eth-TBI mice displayed a marked decrease in the number [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Acute administration of alcohol blocks cocaine induced striatal c-fos immunoreactivity protein in the rat."

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"Experiment 4: Inhibition of the EWcp and ethanol-induced c-Fos."

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"Ethanol also inhibited the Ca2 (+)-dependent induction by anti-IgM of c-fos in these cells."

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"Furthermore, PHY treatment prior to context learning selectively rescued ethanol induced disruptions in prefrontal expression of c-Fos but not Npas4 or Arc, or Egr-1."

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"Acute ethanol exposure significantly reduced the number of orexin neurons containing c-Fos, suggesting an inhibition of orexin neurons after ethanol intake."