IndraLab

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E2~Ub binds OTUB1. 2 / 2

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"In the case of the OTUB1-E2~Ub interaction, we have an unusual example of product inhibition mimicry; the assembly of the Ub~E2-OTUB1-Ub complex completes the formation of a pseudo DUB cleavage product that inhibits a second enzyme, in this case the E2."

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sparser

"A second possible avenue for regulation centres on the role of the distally bound free Ub in the formation of the OTUB1-E2~Ub complex."

22325355

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IndraLab

Statements

E2~Ub binds OTUB1. 2 / 2

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