IndraLab

Statements


OCA2 increases the amount of TNFAIP3. 1 / 1
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"During MeV infection, viral P protein activates the expression of the ubiquitin modifier TNFAIP3, which interacts with TRAF6 binding protein, TAX1BP1, forming a complex that acts as TRAF6 inhibitor by preventing E3 ligase TRAF6 polyubiquitination [XREF_BIBR], thus blocking the TLR4 mediated proinflammatory signaling [XREF_BIBR]."
| PMC