IndraLab
Statements
OTUD5 inhibits interleukin. 1 / 1
|
1
sparser
"Initially, DUBA was found to inhibit PRR‐induced type I interferon production. [ xref ] In addition, DUBA inhibits interleukin (IL)‐17 production in T‐helper type 17 (Th17) cells and thereby attenuates Th17 cell‐mediated intestinal inflammation. [ xref ] Recent studies demonstrate that DUBA controls inflammatory responses by regulating PRR‐induced NF‐κB and MAPK signaling pathways in innate immune cells. [ xref ] However, whether DUBA participates in microglial activation and neuroinflammation remains elusive."