IndraLab

Statements

USP12 decreases the amount of EP300. 4 / 4
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"Second, MG132 treatment, the inhibitor of proteasome, restored silencing USP12-induced downregulation of p300 protein level in NRCMs."
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"Third, the knockdown of USP12 significantly increased levels of p300 ubiquitination, whereas overexpression of USP12 reduced p300 ubiquitination."
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"As showed in Fig. 5 H, overexpression of USP12 reduced the ubiquitination level of p300."
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"But, inhibition of USP12 increased the ubiquitination level of p300 ( Fig. 5 I)."
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