IndraLab

Statements


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sparser
"We found several previously poorly characterized monocyte/macrophage ligand-receptor interactions with lung epithelial cells and other myeloid cells, most apparent at D3, that may be involved in driving later-stage damage and regulating phagocytosis (e.g. TGFB1-ITGB6 and ITGB8, SPP1-ITGAV, SIRP1a-CD47; Fig. 4E )."

reach
"ITGB6 binding to LAP of TGF-beta1 activates the cytokine."

sparser
"In terms of cell cycle, TGFB1-ITGB6, TGFB1-CAV1, TGFB1-CD109 and TGFB1-ACVRL1 were ligand–receptor pairs with remarkable enhancement of communication signals in high PR risk samples, which were mainly sent by endothelial cells, NK cells and myeloid cells and received by malignant hepatocytes ( xref )."

sparser
"In this case, the Warburg effect and ROS generation were enhanced, thereby increasing the potential of cancer metastasis. xref For example, in ovarian cancer, TGFB1ITGB6 can enhance metastasis, lipid metabolism and cisplatin resistance. xref "