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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 activates RELA. 2 / 2

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"Altogether, our findings highlighted that USP7 promoted the occurrence of LN by regulating the NF-kappaB p65 signaling pathway via stabilization of JMJD3."

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"A study reported that USP7 is critical for target gene transcription, whereby USP7 targeted NF-kappaB p65 for K48 linked deubiquitination, increased the protein stability of p65, and ultimately led to increased transcription."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...