IndraLab

Statements

USP18 is phosphorylated. 3 / 3
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sparser
"In contrast to what was observed for human fibroblasts, WT and Isg15 -deficient MEFs accumulated similar levels of phosphorylated Stat2, Ifit2 and Usp18 over the time course of the experiment ( xref )."
27193971
rlimsp
"In contrast to what was observed for human fibroblasts, WT and Isg15-deficient MEFs accumulated similar levels of phosphorylated Stat2, Ifit2 and Usp18 over the time course of the experiment (Fig. 4a)."
27193971
rlimsp
"Specifically, IFN-α induced the phosphorylation of STAT1 and USP18 silencing enhanced the STAT1 activation and phosphorylation for a longer periods of time compared to the control group (Fig 6C), leading to increased expression of ISGs, and thus enhanced the antiviral activity against HBV in Hepg2.2.15 cells."
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