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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP20 activates HIF1A. 2 / 4

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"Up-regulation of Usp20, a deubiquitinase that acts on Hif1a and other proteins 24, should reduce degradation of Hif1a."

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"Therefore, targeting USP20 can induce degradation of HIF-1alpha and be a potential drug target for human cancer."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...