IndraLab

Statements

BAP1 activates Recurrence. 3 / 3
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"Germline or somatic mutations and copy number alterations have been identified in several cancers and inactivation of BAP1 accelerates invasion, recurrence and metastases."
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"Germline or somatic mutations and deletions of BAP1 have been identified in various tumor types, and downregulation or inactivation of BAP1 could accelerate tumor onset, invasion, recurrence, and metastases ."
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"Furthermore, BAP1 has been demonstrated to increase the risk of disease recurrence in patients with resected localized disease: in a cohort of 1479 patients, those with BAP1 loss of function (10.3%) had worse relapse-free survival, even after statistical adjustment for the UISS risk score [49]."
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