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P5091 inhibits Wnt. 3 / 3
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"Taken together, these results are consistent with the findings shown in the cultured cells, suggesting that P5091 inhibits the Wnt signaling and proliferation of colon cancer cells both in vitro and i[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"P5091 attenuates Wnt pathway activity by promoting β-catenin degradation, which inhibits CRC cell proliferation and promotes apoptosis in vitro (214)."
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"These results demonstrated that P5091 has potent anti-tumor activity in vivo without clear toxicity.To determine whether Wnt signaling was also repressed by P5091 in HCT116 xenografts, extracts of tum[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28216017