IndraLab

Statements

Amodiaquine inhibits replication. 3 / 3
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"However, there is evidence that amodiaquine inhibits virus replication of flaviviridae including dengue virus xref and there is also evidence that it interferes with thymidine production xref ."
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"In addition to its antiviral activity determined in viral plaque formation inhibition assay, amodiaquine also inhibited viral replication in growth kinetics assays ( xref )."
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"Careful observation at one Ebola treatment centre determined that malaria treatment (for possible concomitant infection) that included amodiaquine, which inhibits Ebola virus replication in vitro, might be associated with improved survival from Ebola virus disease. xref This hypothesis-generating observational study needs to be investigated further in non-human primate models before being considered for a formal clinical trial."
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