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Statements

Quercetin inhibits IKBKB. 6 / 7
1 | 1 5
sparser
"9 However, the structural basis of IKKβ inhibition by staurosporine and quercetin has not been established yet, and the proposal of their putative binding modes would be of great value to the compreh[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
19896375
sparser
"Quercetin inhibits the purified recombinant IκB kinases, IKK1 and IKK2, by serving as a mixed-type inhibitor versus ATP [16] ."
11543732
reach
"We found that Armepavine, Berberine, Glaucine, Magnoflorine, Reticuline, Quercetin inhibits the growth of diabetic nephropathy by affecting ICAM1, PRKCB, IKBKB, KDR, ALOX5, VCAM1, SYK, TBXA2R, LCK, and F3 genes."
38379386
sparser
"In fact, it has been shown that QUE inhibits both IKKα and IKKβ with apparent IC 50 values of 11 and 4 μM, respectively, reducing the Vmax and increased the Km, indicating a mixed-type of inhibitory m[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26297952
sparser
"Here we demonstrate that quercetin and staurosporine potently inhibit both IKKalpha and IKKbeta."
10551820
sparser
"8 These pharmacological effects are consistent with the strong inhibition of IKKβ by staurosporine (IC 50 = 1.6 μM, K i = 172 nM) and quercetin (IC 50 = 4 μM), reported by Peet and Li in 1999."
19896375