IndraLab

Statements

COPS5 inhibits CUL3. 3 / 3
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"However, by the time the cells initiate this phase, the cytoplasmic CSN5 or Nedd8 proteins could be already used up, preventing the successful execution of the Cullin3 dependent program."
19855832
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"Nevertheless, the csn5 null mutation did not rescue the reduced Cul3 neddylation caused by the lack of Int6 since Cul3 neddylation in the Int6 173-1 -csn5 null double homozygous larvae is very similar to that of the Int6 173-1 single mutant (XREF_FIG, compare lanes 5 and 6)."
18493598
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"Western blot analysis demonstrated that Jab1 deletion increased the abundance of neddylated CUL3."
30301860