IndraLab

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METTL14 activates USP48. 4 / 4
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"For instance, it has been shown that methyltransferase 14, N -adenosine-methyltransferase subunit (METTL14) upregulates ubiquitin specific peptidase 48 to alleviate liver cancer by regulating Sirtuin 6 stability (4)."
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"USP48 is upregulated by Mettl14 to attenuate hepatocellular carcinoma via regulating SIRT6 stabilization ."
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"USP48 is upregulated by Mettl14 to attenuate hepatocellular carcinoma via regulating SIRT6 stabilization."
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"It has been demonstrated that methyltransferase-like 14-induced m6A modification participates in the regulation of USP48 in hepatocellular carcinoma by maintaining Usp48 mRNA stability (43)."
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