IndraLab

Statements

AR activates EP300. 4 / 4
| 3 1
reach
"CBP and p300 increases AR transactivation of the AR in response to androgen or IL-6 (Fronsdal et al., 1998; Debes et al., 2002)."
20541699
reach
"AR S81 phosphorylation has been reported to enhance binding of the histone acetyltransferase EP300 (p300), suggesting that p300 binding and subsequent histone acetylation may drive a positive feedback loop through increased BRD4 recruitment, a subsequent increase in P-TEFb recruitment and further AR S81 phosphorylation."
28062857
reach
"Task 7, ' Passages with GI types (GI evidence passages) ' -- Identification of passages describing GI types, e.g. ' Synergy of FLAP1 and p300 for enhancement of transcriptional activation by beta-catenin, LEF1 and TCF and AR '."
27589962
sparser
"Expression of the coactivators steroid receptor coactivator-1, receptor-associated coactivator-3, and p300 stimulated both agonist-dependent and -independent activation by AR."
11981028