IndraLab

Statements

USP4 inhibits IL1B. 5 / 5
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"Notably, USP4 overexpression antagonized OGD/R-induced IL-1β, IL-6, and TNF-α transcriptional levels (Fig. 3A–C)."
35530618
sparser
"USP4 inhibits IL-1β-, LPS-and TGFβ-induced NF-κB activation."
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"Similarly, USP4 inhibited IL-1β-, LPS- and TGFβ-induced NF-κB production xref ."
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"They showed that endogenous USP4 inhibits IL-1β- and LPS-induced IκBα phosphorylation and pro-inflammatory cytokine expression in various cell types, including HeLa, macrophages (RAW264.7), and mouse [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Additionally, the overexpression of USP4 suppressed the release of microglia activation-induced pro-inflammatory cytokines, including IL-1beta, IL-6, and TNF-alpha."
35530618