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USP15 deubiquitinates FOXC1. 2 / 2
| 2
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"USP15 interacted with and deubiquitinated FOXC1."
40176111
reach
"Additionally, the silencing of FOXC1 ameliorated the therapeutic effect of oe-USP15/Exo on LPS-injured chondrocytes.In summary, our research findings elucidates that USP15-modified ADMSCs-derived Exos induces macrophage polarization towards the M2 phenotype by promoting FOXC1 deubiquitination, thereby effectively reducing the degree of chondrocyte damage in OA."
40176111