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USP19 binds K63- and K27. 1 / 1

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"Mechanistically, USP19 interacted with TAK1 in a TNF-alpha- or IL-1beta-dependent manner and specifically deconjugated K63- and K27 linked polyubiquitin chains from TAK1, leading to the impairment of TAK1 activity and the disruption of the TAK1 and TAB2/3 complex."

31127032

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IndraLab

Statements

USP19 binds K63- and K27. 1 / 1

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