IndraLab

Statements

USP33 deubiquitinates ARRB2. 7 / 7
1 | 6
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"Subsequent deubiquitination of beta-arrestin 2 by the deubiquitinase USP33 dissociates the receptor, beta, and arrestin complex."
19853559
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"USP33 leads to de-ubiquitination of beta-arrestin2 with non degradative effects."
27835898
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"Further results verified that USP33 can deubiquitinate beta-arrestin2, subsequently block the internalization of SDF-1-stimulated CXCR4, and disrupt beta-arrestin-dependent ERK activation."
27835898
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No evidence text available
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"Beta-arrestin-2 can be ubiquitinated by Mdm2 (see above) and deubiquitinated by the DUB enzyme USP33."
20854416
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"Importantly, a knockdown of USP20 and USP33 enhances beta-arrestin2 ubiquitination and increases beta 2 AR degradation [XREF_BIBR, XREF_BIBR]."
24680432
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"Given that the enzymatic activity of USP33 is important in regulating CXCR4 internalization, we were interested in whether USP33 can deubiquitinate beta-arrestin2 and subsequently regulate CXCR4 endocytosis."
27835898