IndraLab

Statements

USP9X activates Neoplasm Metastasis. 9 / 10
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"In vivo studies further substantiate that inhibition of ERK and USP9x suppressed obesity induced metastasis."
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"Inhibition of ERK and USP9x suppressed obesity induced metastasis."
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"Using PANC-1 PC cell line, USP9X was reported to promote tumor metastasis and inhibit tumor apoptosis [ 34 ]."
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"Therefore, USP9X promotes the metastasis of tumor cells76."
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"A patient with cancer of unknown primary site suffering from diffuse bone marrow metastasis and DIC, was treated with FAM (5-fluorouracil, adriamycin and mitomycin C) combination chemotherapy."
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"The family with sequence similarity (FAM) of non-coding RNAs promoted tumorigenesis and metastasis."
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"We next ascertained if the ERK and USP9x pathway observed in cell culture could modulate breast cancer metastasis in obese animal models."
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"In this context, previous publications demonstrated that USP9x-dependent stabilization of insulin receptor substrate 2 or the transcription factors PBX homeobox 1 and ERG supported prostate cancer growth and metastasis [51,52,53]."
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"It was also clarified that aberrant fatty acid metabolism (FAM) might accelerate tumor growth and metastasis of HCC."
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