IndraLab

Statements

USP13 deubiquitinates Cyclin on D1. 5 / 5
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"In this study, we reported for the first time that USP13 stabilized and deubiquitinated cell cycle protein cyclin D1 in GC."
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"USP13 deubiquitinates and stabilizes cyclin D1 to promote gastric cancer cell cycle progression and cell proliferation."
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"To further define whether USP13 deubiquitinated cyclin D1, we transfected USP13 siRNAs or negative control siRNA together with Myc-cyclin D1 and HA-Ub into HEK293T cells and performed Co-IP assays."
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"Taken together, our data demonstrate that USP13 deubiquitinates and stabilizes cyclin D1, thereby promoting cell cycle progression and cell proliferation in GC."
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"USP13 interacted with and deubiquitinated cyclin D1."
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