IndraLab

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Propofol inhibits FOS. 6 / 7
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"Taken together, these results suggested that propofol inhibited Arc and c-Fos, two downstream products pending on PARP-1 activation, at both protein and mRNA levels.Val762Ala lies within the catalytic[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26921778
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"Propofol inhibited c-Fos and Arc in brain, which has been recognized as molecular mechanisms of propofol induced cognitive dysfunction (Kozinn et al., 2006; Ren et al., 2008; Whittington et al., 2013)[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Propofol dose dependently suppressed the c-Fos positive ratio of CRF neurons (86±18%, 78±17% and 17±15%, for 0, 0.1 and 0.2 mg/kg/min propofol, respectively; P <0.0001)."
15496295
sparser
"Propofol inhibited c-Fos and Arc in brain, which has been recognized as molecular mechanisms of propofol-induced cognitive dysfunction ( Kozinn et al., 2006; Ren et al., 2008; Whittington et al., 2013[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26921778
reach
"Stimulation with 250 µM or 500 µM propofol decreased NFATc2, Sp1 and cFos signalling in the Western blot analysis."
37909980
sparser
"Taken together, these results suggested that propofol inhibited Arc and c-Fos, two downstream products pending on PARP-1 activation, at both protein and mRNA levels."
26921778