IndraLab

Statements


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sparser
"These results show that the tripartite interaction between Notch, DTX, and eIF3f occurs preferentially with activated, membrane-associated, but γ-secretase unprocessed, forms of Notch."

reach
"These results show that the tripartite interaction between Notch, DTX, and eIF3f occurs preferentially with activated, membrane associated, but gamma-secretase unprocessed, forms of Notch."

sparser
"We show that Notch is only able to interact with eIF3f in the presence of the E3 ubiquitin ligase DTX and that a monoubiquitinated form of Notch is probably the substrate targeted by the DUB."

sparser
"With the help of another protein called Deltex1, which acts as a matchmaker, eIF3f associates with Notch when it is in the cell membrane, carrying a single ubiquitin protein."

sparser
"The activated form of Notch is able to interact with eIF3f only in the presence of the E3 ubiquitin ligase Deltex [ xref ]."