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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

USP25 inhibits GLI1. 3 / 3

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"USP21 is able to interact with GLI1, thereby suppressing GLI1 dependent transcription."

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"Likewise, overexpression of GFP-USP21 inhibited Gli1 transcriptional activity to a similar degree, and this inhibition depended on its catalytic activity (XREF_FIG C)."

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"In this assay, siRNA mediated depletion of USP21 decreased Gli1 transcriptional activity by ~ 40% (XREF_FIG B)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

USP25 inhibits GLI1. 3 / 3

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