IndraLab

Statements


RNF168 ubiquitinates KCNG1. 5 / 5
| 5

sparser
"The E3 ligase RNF168 ubiquitylates H2A on both K13 and K15 (refs. xref , xref )."

sparser
"The K63-linked polyubiquitin chains recruit the E3 ubiquitin ligase RNF168, which ubiquitylates histone H2A on K13 and K15 [ xref , xref ]."

sparser
"These results indicate that RNF168 preferentially ubiquitinates the K13 and K15 sites of nucleosome H2A in vitro [ xref , xref ]."

sparser
"RNF168, in turn, ubiquitylates H2A K13 and K15 residues, thus promoting the subsequent recruitment of repair enzymes [ xref , xref , xref , xref ]."

sparser
"While RNF168 can ubiquitylate H2A K13 or K15 in vitro and in vivo xref , xref , we tested whether 53BP1 displayed selectivity towards K13ub or K15ub."