IndraLab

Statements

TUDCA inhibits CASP1. 2 / 2
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"It was found that TUDCA treatment could repress BSA induced activation of caspase-1 as determined by immunoblotting for the active p10 subunit as shown in XREF_FIG."
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"Treatment with TUDCA, a molecular chaperone that alleviates ER stress, and 4μ8C, IRE1α inhibitor that selectively inactivates RNase activity, decreased Bid truncation, caspase-2 and caspase-1 cleavages, and IL-1β production in RB51-infected or ER stress inducer-treated BMDM, but not LPS + ATP-treated BMDM [41]."
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