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USP14 activates CDK4. 1 / 1

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"Our experiments showed that CDK4, CDK6, CDK2, cyclinD1 and phosphorylated Rb were downregulated, while p27 and p15 were increased, by inhibiting USP14 expression or its activity in androgen responsive prostate cancer cells; and conversely, the exactly opposite changes were induced by USP14 overexpression."

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USP14 activates CDK4. 1 / 1

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