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OTUD3 inhibits RLR. 2 / 2
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"Interestingly, the deubiquitinating enzyme OTUD3 promotes cGAS-mediated DNA sensing but inhibits RLR-mediated RNA sensing ."

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"These results indicated that OTUD3 might repress RLR signaling by interfering with MAVS.To confirm this hypothesis, we performed co-immunoprecipitation assays that showed ectopically expressed OTUD3 C[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"