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USP21 inhibits adipose tissue inflammation-related SERPINE1 PAI-1 adipocyte protein aP2 HMGA4high mobility group protein A2 HMGA2 matrix metalloproteases. 1 / 1
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"We previously demonstrated that in human macrophage-like HL-60 cells , USP2-1 suppressed the expression of adipose tissue inflammation-related genes for SERPINE1 PAI-1 , adipocyte protein 2 ( aP2 ) , HMGA4high mobility group protein A2 ( HMGA2 ) , and matrix metalloproteases ( MMPs ) [ 9 ] ."