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TNF increases the amount of CYLD. 12 / 15
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"Indeed, both TNF-alpha and non typeable Haemophilus influenzae (NTHi), a common Gram negative bacterial pathogen that causes respiratory infections, can upregulate CYLD expression, suggesting that CYL[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
20347313
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"32 In mouse bone marrow derived macrophages, CYLD expression is strongly induced by RANKL, but not by TNF-alpha or LPS."
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"In the present study, we found that both LPS and TNF-α did not increase the mRNA level of CYLD."
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"At this time, the underlying mechanism by which TNFalpha up-regulates the expression of CYLD is not clear."
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"Such a function of CYLD was suggested by the finding that the expression of CYLD is induced by proinflammatory cytokines, TNF-alpha and IL-1beta, and the Gram negative bacterium Haemophilus influenzae."
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"Several early reports indicated that CYLD expression was upregulated by LPS or TNF-α treatment [31–33]."
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"In cultured human tubular epithelial HK-2 cells, tumor necrosis factor-alpha (TNFalpha) up-regulated CYLD expression."
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"Similarly, mRNA levels of CYLD or cIAP1, which are involved in the regulation of complex I activity (Annibaldi & Meier, 2018), were not significantly induced by TNF or reduced in RelA-knockout cells (Fig XREF_FIG)."
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"The expression of CYLD can be induced by TNF treatment or viral infection (Friedman et al., 2008) ."
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"The expression of CYLD and NF-kappaB mRNAs in HSG cells was increased by TNF-alpha."
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"For example, although TNF-alpha stimulates CYLD expression in HeLa cells, human bronchial epithelial cells, and human aortic endothelial cells, XREF_BIBR - XREF_BIBR it fails to induce CYLD expression in 293 cells."
19373246
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"One possibility is that Cyld expression is upregulated by TNF and IL-1beta, via IKK-NF-kappaB pathway XREF_BIBR, XREF_BIBR, XREF_BIBR triggers its association with Itch."
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