IndraLab

Statements

USP3 deubiquitinates H2AC20. 3 / 4
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"USP3 dynamically associates with chromatin and deubiquitylates uH2A/uH2B in vivo ."
20685273
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"The involvement of USP3 in DDR was first reported in 2007 by Nicassio et al. 32 According to their findings, USP3 is essential for the complete deubiquitylation of uH2A/H2B and γ‐H2AX through its enzymatic catalytic activity."
38651282
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"Further studies revealed that in addition to uH2A, USP3 also deubiquitinates conjugate Ub-γH2AX (variant H2A) at K13-15."
38773075