IndraLab

Statements

TRIM21 binds USP4. 10 / 14
4 1 | 2 3
sparser
"The proteasome has both ubiquitin ligases and DUBs that associate with it (Crosas et al., 2006) , and several DUB-ligase pairs interact directly, including BRCC36-BRCA1, BAP1-BRCA1, USP4-Ro52, USP7-MDM2, USP8-GRAIL, USP20-pVHL, USP33-pVHL and USP44-APC (Kee and Huibregtse, 2007; Marfany and Denuc, 2008; Ventii and Wilkinson, 2008) ."
19571111
biogrid
No evidence text available
16472766
sparser
"The two proteins were shown to co-localize to cytoplasmic rod-like structures in HEK293 cells, suggesting that Ro52 interacts with USP4 in mammalian cells to form a heteromeric protein complex that mediates both ubiquitination and deubiquitination of substrates [ xref ]."
18687060
reach
"Another possibility is that the Ro52 and Usp4 complex regulates the movements of the cytoplasmic bodies by ubiquitination and deubiquitination."
20013343
biogrid
No evidence text available
11461834
hprd
No evidence text available
11461834
reach
"The two proteins were shown to co-localize to cytoplasmic rod like structures in HEK293 cells, suggesting that Ro52 interacts with USP4 in mammalian cells to form a heteromeric protein complex that mediates both ubiquitination and deubiquitination of substrates [XREF_BIBR]."
18687060
biogrid
No evidence text available
23105109
biogrid
No evidence text available
16403452
sparser
"For example, USP4 associates with the E3 ligase Ro52 forming, as observed here for dUSP36-D and AGO, a DUB/E3 ligase pair that transregulates each other by ubiquitination and deubiquitination ( xref )."
32637412