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USP13 activates USP13. 3 / 4
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"We further demonstrated that Casein kinase 2 (CK2) directly interacts with and phosphorylates USP13 at Thr122, which promotes the stability of USP13 protein."
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"Overexpression of USP13 in PC12 cells almost reversed the Spautin‐1‐mediated decrease in NLRP3, USP13, Beclin1 and GSDMD‐N expression levels (Figure 3D,E)."
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"( D ) Hypoxia increased USP13 , TLR4 , MyD88 , and P-NF-kappaB p65 proteins , which was subsequently reduced by USP13 knockdown ."
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