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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP13 activates USP13. 3 / 4

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"We further demonstrated that Casein kinase 2 (CK2) directly interacts with and phosphorylates USP13 at Thr122, which promotes the stability of USP13 protein."

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"Overexpression of USP13 in PC12 cells almost reversed the Spautin‐1‐mediated decrease in NLRP3, USP13, Beclin1 and GSDMD‐N expression levels (Figure 3D,E)."

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"( D ) Hypoxia increased USP13 , TLR4 , MyD88 , and P-NF-kappaB p65 proteins , which was subsequently reduced by USP13 knockdown ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...