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Mutated KRAS activates COPS6. 1 / 1

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"Because KRAS is an upstream regulator of these two pathways, KRAS mutations will continue to activate both RAS-MAPK and AKT pathways to stabilize CSN6, which in turn activates beta-catenin activity to cause pathogenesis in colon cancer."

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IndraLab

Statements

Mutated KRAS activates COPS6. 1 / 1

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