IndraLab

Statements

USP10 decreases the amount of ubiquitinated CFTR. 3 / 3
| 3
reach
"Overexpressing USP-10 decreased the amount of ubiquitinated CFTR and increased its abundance in the plasma membrane of human airway epithelial cells [XREF_BIBR]."
21146391
reach
"small interference RNA mediated knockdown of USP10 increased the amount of ubiquitinated CFTR and its degradation in lysosomes, and reduced both apical membrane CFTR and CFTR mediated chloride secretion."
19398555
reach
"Moreover, a dominant negative USP10 (USP10-C424A) increased the amount of ubiquitinated CFTR and its degradation, whereas overexpression of wt-USP10 decreased the amount of ubiquitinated CFTR and increased the abundance of CFTR."
19398555