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SCN10A inhibits sodium(1+). 2 / 2

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"Mutations in the SCN10A gene that encodes the Nav1.8 sodium channel, were detected in BrS-patients and were demonstrated to reduce peak sodium current (I ) in the human-induced pluripotent stem cell-derived cardiomyocytes derived from a BrS-patient [7]."

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"Furthermore, they demonstrated that the SCN10A variants R1268Q and R14L reduced cardiac sodium currents."

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SCN10A inhibits sodium(1+). 2 / 2

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