
IndraLab
Statements
Wedelolactone inhibits IKBKB. 5 / 7
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"To determine if the rapid induction of apoptosis in macrophages and DC was NF-κB/IKK inhibition-dependent and not an off-target effect of TAT-NBD, five additional NF-κB inhibitory compounds were tested: Compound A (CmpA) and TPCA-1, both of which inhibit IKKβ; MG-132, which inhibits IκBα proteosomal degradation; and IKKiVII and Wedelolactone, which inhibit both IKKα and IKKβ (see xref )."