IndraLab

Statements

Simvastatin inhibits IRF3. 2 / 2

| 2

reach

"Furthermore, GGPP recovered the statin suppressed IRF3 and JAK and STAT signaling in poly (I : C)-treated macrophages."

33452755

➶

reach

"Independent of mevalonate and NF-kappaB, previously acknowledged anti-inflammatory mechanisms of pleiotropic statins, simvastatin selectively inhibited dsRNA induced IRF3 activation and production of TSLP and IFN-beta in COPD epithelium."

22881993

INDRA sources:

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IndraLab

Statements

Simvastatin inhibits IRF3. 2 / 2

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