IndraLab

Statements

CYLD activates AP1. 4 / 4
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reach
"In addition, CYLD WT markedly reduced while CYLD m significantly potentiated AP1 activity driven by exogenous c-Fos expression; conversely, gene silencing of c-Jun or c-Fos abolished AP1-induction by CYLD m (XREF_FIG)."
21478324
sparser
"Thus, the exact mechanism of MALT1- and CYLD-dependent AP-1 activation and the role of JNK in this pathway remain to be further explored."
26507244
reach
"We found that CYLD m increased AP1 driven expression both in the presence and absence of EGF; whereas CYLD WT reduced AP1 activity in both conditions (XREF_FIG)."
21478324
reach
"CYLD Inhibits Tumorigenesis and Metastasis by Blocking JNK and AP1 Signaling at Multiple Levels."
21478324