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Geldanamycin inhibits IRF3. 2 / 3

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"Tilorone, tilorone 874, acridine orange and geldanamycin blocked the activation of IRF-3 induced by poly (I : C) but not by LPS, indicating distinct signaling pathways are activated by these stimuli.I[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

12062447

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"Taken together, these results suggest that geldanamycin and 17-AAG inhibit IRF3 activation by preventing MAVS aggregation on the mitochondria."

21782231

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IndraLab

Statements

Geldanamycin inhibits IRF3. 2 / 3

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