IndraLab

Statements

Baicalin inhibits TLR7. 5 / 5
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"Baicalin inhibits TLR7 and MYD88 signaling pathway activation to suppress lung inflammation in mice infected with influenza A virus."
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"In conclusion, baicalin effectively reduced the pathological damage and inflammation of the lungs by downregulating the TLR7 and MYD88 mediated signaling pathway."
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"These observed changes suggest that the primary mechanism of baicalin (1) in antiviral in inhibiting immunologic injury involves inhibiting NF-κB and TLR7/MyD88 pathway, followed by reducing the inflammatory cytokine expression."
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"Wan and colleagues [XREF_BIBR] demonstrated that baicalin inhibits TLR7 and MYD88 signaling pathway activation to suppress lung inflammation in mice infected with influenza A virus."
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"Baicalin inhibits NA (Ding et al., 2014; Jin et al., 2018) and TLR7/MYD88 signaling pathway activation to suppress inflammation in mice infected with influenza A virus (Wan et al., 2014)."
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