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"It has been proposed that the IBTX-mediated inhibition of BK channel results in VSMC depolarization and, thereby, increases the opening of the voltage-activated L-type calcium channels ( Xu et al., 20[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"These results suggest that, in the absence of calcium, the Slo1 tail inhibits voltage dependent gating, and that calcium removes this inhibition."

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"Phosphorylation of the BK channel by cGMP kinase lowers its voltage and Ca 2+ activation threshold."

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"Thus, this BK channel shares functional and possibly structural homologies with other inactivating voltage gated potassium channels."