IndraLab

Statements


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"USP2 inhibition causes cell cycle arrest in activated cardiac fibroblasts ."

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"Taken together, these results demonstrate that USP2 mediated cell cycle control occurs primarily through its effect on cyclin D1, regardless of p53 status."

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"USP2 modulates cell cycle progression, and therefore carcinogenesis, via the deubiquitination of cyclins and Aurora-A."

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"USP2 modulates cell cycle progression , and therefore carcinogenesis , via the deubiquitination of cyclins and Aurora-A ."

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"To test this hypothesis, we first examined cell cycle distribution in cells treated with control versus USP2 siRNAs."

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"In addition, USP2 inhibition suppressed CFs proliferation, collagen synthesis and cell cycle progression."

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"In addition , USP2 inhibition suppressed CFs proliferation , collagen synthesis and cell cycle progression ."

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"Within this group, Usp2 activates Wnt signaling [17]; Rab35 is a GTPase that regulates phosphoinositides and F-actin on endosomes [18]; Grtp1 is a Rab-GAP with broad specificity [19]; and Casp6 regula[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"