IndraLab

Statements


USP25 deubiquitinates MAP2K2. 5 / 5
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"Conversely, USP21 inhibition increased MEK2 ubiquitylation in cells."

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"XREF_FIG, wild type USP21 decreased MEK2 ubiquitination, whereas the C221A USP21 deubiquitinase deficient mutant failed to do so."

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"USP21 deubiquitinates and stabilizes MEK2, which contributes to tumorigenesis ."

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"Since USP21 functions as a deubiquitylase, we next ask whether USP21 deubiquitylates MEK2."

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"USP21 deubiquitylates MEK2."