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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

CYLD activates PSD. 2 / 2

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"By immunoEM, CYLD has been shown to be present at the PSD and to accumulate further upon depolarization XREF_BIBR, suggesting a potential role of CYLD in activity induced modification of PSD."

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"Thus accumulation of CYLD at the PSD following synaptic activity may remove lysine63 linked polyubiquitin chains from proteins and thus prevent trafficking and autophagic degradation of PSD components."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...