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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

GAP binds mTORC1, RHEB, TSC1, and TSC2. 2 / 2

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"Most of these signals exert their effect on mTORC1 by modulating the activity of the tuberous sclerosis complex proteins, TSC1 and TSC2, which form a heterodimer that functions as a GTPase activating protein (GAP) to inhibit the activity of the small GTPase Rheb ( xref )."

18762019

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sparser

"Most of these signals exert their effect on mTORC1 by modulating the activity of the tuberous sclerosis complex proteins, TSC1 and TSC2, which form a heterodimer that functions as a GTPase activating [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

18762019

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...