IndraLab

Statements



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"We observed that the activity and protein levels of both HDAC1 and HDAC4 are decreased when myoblast differentiation is promoted by the USP4 knockdown."

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"Ubiquitin specific protease 4 (USP4) suppresses myoblast differentiation by down regulating MyoD activity in a catalytic independent manner."

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"USP4 suppresses Wnt3a induced osteoblast differentiation and mineralization by cleaving K63 linked polyubiquitin chains from disheveled (Dvl) and inhibiting the accumulation of beta-catenin and activation of its downstream cascades."

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"Naive CD4 + T cells were sorted using flow cytometry based analysis and were induced for Th2 cell differentiation, and were treated with the inhibitor of USP4, vialinin A, and then processed by flow cytometry."