IndraLab

Statements

CACNA1A activates NMDAR. 3 / 3
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sparser
"NMDA receptors directly gate calcium flux while AMPA receptors indirectly control calcium by regulating the voltage-dependent activation of NMDA receptors and voltage-sensitive calcium channels."
12951163
sparser
"On the other hand, epileptogenic transformation of the intact hippocampal neuronal network required voltage-dependent activation of NMDA-Rs and long-term alterations in GABAergic synapses, which became excitatory because of a positive shift in the chloride reversal potential ( xref )."
20810895
sparser
"Instead, it shows that the outward rectification of synaptic α5-GABA A Rs is essential to counteract the slow and voltage-dependent activation of NMDARs above –50 mV."
30177704