IndraLab

Statements

CACNA1A activates NMDAR. 6 / 6
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"The glutamate stimulates distal dendritic AMPA receptors to increase spontaneous EPSCs and enabled a voltage-dependent activation of neuronal NMDA receptors."
11976371
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"As we were not able to block this component, we could not test or rule out a potential contribution to voltage-dependent activation of NMDA receptors in the young neurons."
28826488
sparser
"Instead, it shows that the outward rectification of synaptic α5-GABA A Rs is essential to counteract the slow and voltage-dependent activation of NMDARs above –50 mV."
30177704
sparser
"On the other hand, epileptogenic transformation of the intact hippocampal neuronal network required voltage-dependent activation of NMDA-Rs and long-term alterations in GABAergic synapses, which became excitatory because of a positive shift in the chloride reversal potential ( xref )."
20810895
sparser
"A slow mode, which is seen in the isolated hemicord activated with NMDA, depends on slow bursting sustained by the voltage-dependent activation of NMDA receptors, while a fast mode is seen during application of d -glutamate and does not require NMDA voltage-dependent activation ( xref )."
21111210
sparser
"NMDA receptors directly gate calcium flux while AMPA receptors indirectly control calcium by regulating the voltage-dependent activation of NMDA receptors and voltage-sensitive calcium channels."
12951163