IndraLab

Statements

Berberine inhibits IKBKB. 7 / 7
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"We found that Armepavine, Berberine, Glaucine, Magnoflorine, Reticuline, Quercetin inhibits the growth of diabetic nephropathy by affecting ICAM1, PRKCB, IKBKB, KDR, ALOX5, VCAM1, SYK, TBXA2R, LCK, and F3 genes."
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"Berberine could inhibit IKK-beta leading to the stabilized IkappaB-alpha."
30100874
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"The results showed that berberine downregulated MAPK1, STAT3, CDK2, IKBKB, HRAS, FOXO3, RAC serine/threonine protein kinase 2 (AKT2), AKT3, FOXO4, polo-like kinase 4 (PLK4), enolase 1 (ENO1), and HIF-1 α (p < 0.001)."
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"In contrast, the same concentration of berberine only inhibited the activity of IKK-beta by 14% in the current study, which suggested that the assay method used in the current study was not as sensitive as the immunocomplex kinase assay."
26937251
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"B-α) was phosphorylated by IKK-β and then degraded, inhibition of IKK-β by berberine could result in the stabilization of I??"
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"9 : Berberine is able to reduce inflammatory cytokines expression and inhibit activation of IKK-beta (ser181) in obese mice, which may partly explain the therapeutic effect of berberine on insulin resistance and abnormal glucose metabolism."
20822024
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"Berberine could inhibit IKK-β leading to the stabilized IκB-α (Lee et al., xref ; Jia et al., xref ; Li et al., xref )."
30100874